A bizarre historical experiment in tarnsplantation surgery

In the late 1940s and early 1950s Soviet-Russian scientist Vladimir Demikhov conducted pioneering experiments in the field of transplantation surgery.

At that time, medical science had little knowledge of graft-versus-host disease and had no antirejection drugs. However, the work of Demikhov was one of the first significant steps towards today's successful transplantation surgery.

Another notable Soviet-Russian medical scientist of the time was Sergei Brukhonenko who made successful experiments in maintaining circulation and perfusion extracorporaly.